Mimi Rogers, Nicole Kidman and Katie Holmes were all in their early thirties when their marriages to the Hollywood leading man took a turn for the worse.
Fans of the heartbroken star searched for a meaning, some postulating that the number 33 is related somehow to Tom Cruise's religion, Scientology.
Tom Cruise married Mimi Rogers when she was 31 in May of 1987. She was 33 when they broke up in 1990. In his second marriage to Nicole Kidman, the actors stayed together for ten years. They split in 2001, when she was 33.
His wedding with Katie Holmes was in 2006 when she was 28 and this week, when she filed for divorce, she had reached the age of 33. In each case, divorce proceedings began when the wives were 33 and concluded when the were 34
There is a belief in the church of Scientology that marital problems come from 'withholds' or 'overts' - undiscussed issues or problems.
Katie Holmes is believed to have blind-sided her Mission Impossible star husband by initiating divorce proceedings and seeking sole custody of their daughter Suri.
With sole custody of Suri, Mrs Holmes would be able to remove her daughter from the Church of Scientology despite her husband's enthusiasm for it.
The estranged couple have been raising Suri in accordance with the doctrine of the Church of Scientology - treating her as an adult, free to make her own decisions.